During Prohibition in the 1920s, the U.S. federal government tried to outlaw the sale of booze, wine and beer, and that didn't go over very well. By mid-decade, officials in the administration of President Calvin Coolidge were frustrated because so many Americans continued to drink bootlegged alcohol. They decided upon a devious -- or rather, murderous -- tactic. Knowing that millions of gallons of industrial alcohol were being stolen by bootleggers and used to make beverages, they ordered manufacturers in 1926 to add poisons such as formaldehyde, chloroform and methyl alcohol to their products.
Quickly, illicit drinkers began dying in droves, and the toll became so shocking that New York City medical examiner actually held a press conference to warn the public about the plot. "The United States government must be charged with the moral responsibility for the deaths that poisoned liquor causes, although it cannot be held legally responsible," he railed.
It did little good. Four hundred people died in New York alone from poisoned booze, and the following year, the death toll climbed to 700. The fiendish deterrent program didn't stop until Prohibition was repealed in December 1933 [source: Blum].